Thinking through Pathology

The anatomy and pathology of Diffuse Lung Diseases (DLD) are presented in the following pages, together with example images. Please remember that the purpose of the discussion (and of the entire website) is not a thorough illustration of the matter, rather a synthetic showing of the main topics dealt with during the Course, to help its pupils to refresh its contents.

The anatomy of the pulmonary secondary lobule and its components is the first milestone to get familiar with the pathology of DLD.

The subsequent aim should be getting acquainted with the elementary lesions that populate the lobule in pathological conditions: inflammation, fibrosis, neoplasm, miscellanea.

The final step is learning how to approach the diseases, which is not trivial when facing the kaleidoscopic world of the ILDs. The task may be achieved with an eye both on the site of the disease within the lobule and on the main constituent cells of the lesions, in mutual synergy, better starting from a selected number of patterns.

Conceptually, the pathologic patterns have the same meaning as the radiologic ones, e.g., that of allowing a quick but solid identification of an underlying pathology through characteristic elements. As always, when trying to pigeonhole complex matter, oversimplification and chance of errors are around the corner, so the suggestion to always compare pathological findings with radiological and clinical data is a golden rule.